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S Marc Breedlove Selected Research

Androgen-Insensitivity Syndrome (Testicular Feminization)

1/2019Oestrogen and androgen receptor activation contribute to the masculinisation of oxytocin receptors in the bed nucleus of the stria terminalis of rats.
3/2014New knockout model confirms a role for androgen receptors in regulating anxiety-like behaviors and HPA response in mice.
7/2013Androgen receptors mediate masculinization of astrocytes in the rat posterodorsal medial amygdala during puberty.
9/2011Male rats with the testicular feminization mutation of the androgen receptor display elevated anxiety-related behavior and corticosterone response to mild stress.
4/2011The organizational role of testicular hormones and the androgen receptor in anxiety-related behaviors and sensorimotor gating in rats.
1/2011Prenatal flutamide enhances survival in a myogenic mouse model of spinal bulbar muscular atrophy.
9/2010Minireview: Organizational hypothesis: instances of the fingerpost.
7/2010Neonatal androgen-dependent sex differences in lumbar spinal cord dopamine concentrations and the number of A11 diencephalospinal dopamine neurons.
8/2009Androgen regulates the sexually dimorphic gastrin-releasing peptide system in the lumbar spinal cord that mediates male sexual function.
11/2008Mice with the testicular feminization mutation demonstrate a role for androgen receptors in the regulation of anxiety-related behaviors and the hypothalamic-pituitary-adrenal axis.
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S Marc Breedlove Research Topics

Disease

13Androgen-Insensitivity Syndrome (Testicular Feminization)
01/2019 - 06/2005
7X-Linked Bulbo-Spinal Atrophy
01/2020 - 11/2007
7Muscular Atrophy (Muscle Atrophy)
03/2019 - 01/2011
4Neuromuscular Diseases (Neuromuscular Disease)
01/2020 - 07/2015
4Feeding and Eating Disorders (Eating Disorder)
05/2013 - 04/2006
3Attention Deficit Disorder with Hyperactivity (Attention Deficit Hyperactivity Disorder)
09/2010 - 02/2008
3Congenital Adrenal Hyperplasia (Hyperplasia, Congenital Adrenal)
09/2010 - 12/2002
2Disease Progression
01/2020 - 01/2018
2Post-Traumatic Stress Disorders (Post Traumatic Stress Disorder)
01/2018 - 01/2018
2Wounds and Injuries (Trauma)
01/2018 - 01/2018
2Myotonic Dystrophy (Dystrophia Myotonica)
01/2016 - 04/2015
2Muscle Weakness
04/2015 - 11/2007
1Cryptorchidism (Undescended Testes)
01/2022
1Communicable Diseases (Infectious Diseases)
10/2021
1Neurodegenerative Diseases (Neurodegenerative Disease)
07/2014
1Tetanus
06/2013
1Motor Neuron Disease (Primary Lateral Sclerosis)
06/2013
1Perinatal Death
01/2011
1Autistic Disorder (Autism)
09/2010
1Attention Deficit and Disruptive Behavior Disorders (Disruptive Behavior Disorder)
04/2009
1Mood Disorders (Mood Disorder)
04/2009
1Erectile Dysfunction
01/2009
1Atrophy
11/2007
1Schizotypal Personality Disorder
09/2006
1Schizophrenia (Dementia Praecox)
09/2006

Drug/Important Bio-Agent (IBA)

17Androgen Receptors (Androgen Receptor)IBA
07/2016 - 06/2005
13AndrogensIBA
01/2022 - 12/2002
5Testosterone (Sustanon)FDA Link
01/2018 - 04/2006
4polyglutamineIBA
07/2016 - 11/2007
3Gonadal HormonesIBA
01/2018 - 09/2006
3Hormones (Hormone)IBA
01/2018 - 03/2008
2Nerve Growth Factors (Neurotrophins)IBA
01/2020 - 07/2015
2Dexamethasone (Maxidex)FDA LinkGeneric
01/2018 - 01/2018
2CorticosteroneIBA
01/2018 - 09/2011
2Messenger RNA (mRNA)IBA
04/2015 - 08/2009
2Flutamide (Eulexin)FDA LinkGeneric
07/2014 - 01/2011
2Proteins (Proteins, Gene)FDA Link
08/2009 - 05/2008
2Estradiol (Delestrogen)FDA LinkGeneric
04/2009 - 04/2006
1Immunoglobulin D (IgD)IBA
01/2022
1HLA Antigens (Human Leukocyte Antigens)IBA
10/2021
1Brain-Derived Neurotrophic Factor (BDNF)IBA
01/2020
1Valproic Acid (Depakote)FDA LinkGeneric
01/2019
1Glucocorticoid Receptors (Glucocorticoid Receptor)IBA
01/2018
1Sucrose (Saccharose)IBA
01/2018
1Protein Isoforms (Isoforms)IBA
01/2016
1Sodium Channels (Sodium Channel)IBA
01/2016
1Conotoxins (Conotoxin)IBA
01/2016
1Chloride Channels (Chloride Channel)IBA
04/2015
1Androgen Antagonists (Antiandrogens)IBA
07/2014
1Anti-Anxiety Agents (Anxiolytics)IBA
03/2014
1Polymethyl Methacrylate (Sol)IBA
06/2013
1Mutant Proteins (Protein, Mutant)IBA
06/2013
1salicylhydroxamic acid (SHAM)IBA
04/2011
1Gastrin-Releasing PeptideIBA
01/2009
1Biological FactorsIBA
03/2008
1SteroidsIBA
02/2008
1Estrogens (Estrogen)FDA Link
04/2006

Therapy/Procedure

1Therapeutics
01/2018
1Electrodes (Electrode)
01/2016
1Castration
08/2009